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Description

Doses up to 500 mg seem well tolerated, and several studies have used even higher doses without any serious side effects ( Because CoQ10 is a fat-soluble compound, its absorption is slow and limited

Secondary analyses were conducted by instrument (HDRS, BDI, MADRS)

This remarkable selectivity stems from 5-amino-1MQs specific interaction with the nicotinamide-binding pocket of NNMT, rather than the SAM-binding site common to many methyltransferases