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( 3.1.2 Active immune recognition interferes with innate immune responses MP can synthesize capsular polysaccharides (CPS) similar to those on host cell surfaces, forming a physical barrier that conceals its highly immunogenic LAMPs and lipopeptides from TLR recognition ( in vitro to induce IL-10 secretion and inhibit dendritic cell maturation via the DC-SIGN pathway (65)

Piperlongumine inhibits thioredoxin reductase 1 by targeting selenocysteine residues and sensitizes cancer cells to erastin

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Because tiotropium is a predominantly renally excreted drug, patients with moderate to severe renal impairment (creatinine clearance of 3% in the STIOLTO RESPIMAT treatment group and a higher incidence rate than the active comparator groups listed