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392 FMD, a 5-day fasting dietary pattern, increases cardiac vascularity and function and resistance to cardiotoxins in a high-fat, high-calorie diet (HFCD) mouse model, thereby postponing the process of cardiac aging

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Since the main physiological role of DME and DT is to dispose of various endogenous compounds, some studies in recent years have proposed to characterize the activity of DME and DT by detecting changes in the levels of these biomarkers, which has been well applied in the early DDI studies of drug discovery [174]