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Description

In a concentration range compatible with the nocturnal surge (pM to nM), melatonin orchestrates a plethora of physiological functions by activating GPCRs receptors (MT1 and MT2) localized in plasmatic, nuclei and mitochondrial membranes

Ji et al., 2019

Rubio, N., Fleury, S

DOI: 10.3390/biology5040037 173

ICP is relatively low under normal physiological conditions, exhibiting only small fluctuations, so changes in MAP are usually the main determinant of CPP