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The central clinical idea: when mitochondrial ATP production falls and oxidative stress rises, the brain may lose the energy and antioxidant reserve needed to regulate neurotransmission, maintain cell membranes, recycle methionine, produce SAM, clear adenosine and homocysteine, build glutathione and tolerate medications or supplements

10.1038/s41467-021-26052-x 123 LiuS.YuB.WangS.ShenY.CongH

External links [edit] Frank Grillo at IMDb 1965 births Living people 20th-century American male actors 21st-century American male actors American male film actors American male soap opera actors American male television actors American male voice actors American people of Italian descent American practitioners of Brazilian jiu-jitsu Male actors from Rockland County, New York Male actors from the Bronx Male models from New York (state) New York University Stern School of Business alumni

Nazha A, Kantarjian HM, Ravandi F, Xuelin H, Choi S, Garcia-Manero G, Jabbour E, Borthakur G, Kadia TM, Konopleva M, Cortes JE, Ferrajoli A, Kornblau SM , Andreeff M, Du M, Brand M, Faderl SH

Functionally, through this interaction, D2R recruits DAT to plasma membrane and therefore enhances the reuptake of dopamine