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doi: 10.1016/j.joen.2015.01.024 8 AnluW.DongchengC.HeZ.QiuyiL.YanZ.YuQ.et al

Due to this mechanism of action, acetylcysteine is also indicated as a specific antidote in paracetamol poisoning and in the course of treatment of cyclophosphamide-induced hemorrhagic cystitis, in the latter case, it provides the -SH groups necessary to inactivate acrolein, a toxic metabolite that affects the urinary mucosa, whilst not interfering with chemotherapy