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A conserved serine residue (Ser167 in HPII) is also found to be hydrogen bonded to the N of the essential histidine and might facilitate the enzymatic mechanism [46]

10.1073/pnas.86.10.3901 119 LindqvistD.DhabharF

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boulardii can enhance the catalytic activity of major antioxidant enzymes, notably superoxide dismutase, glutathione peroxidase, and catalase in liver tissue, and reduce the accumulation of oxidative stress products such as malondialdehyde and protein carbonyls

If the exposure is high dose radiation, the dosage should be continued for 6 months