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coli BL21 cell s transformed with the CRM1 expression construct

It commonly occurs on the face, neck, back, buttocks and chest

After the formation of DQ, the pathway diverges into two pathways leading to the synthesis of reddish-yellow pheomelanin that requires the presence of cysteine, or brownish-black eumelanin due to adding an amino group to DQ with tyrosinase-related proteins 1 (TYRP1) and 2 (TYRP2) or dopachrome tautomerase (DCT)