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Evidence of increased glutamate levels have been observed in patients suffering from TLE and in preclinical seizure models (Figure 1)

Notably, certain synthetic and natural agents exhibit the capacity to disrupt glutathione dynamics and enzyme function

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As one of the most fundamental intracellular antioxidants, it neutralizes reactive oxygen species (ROS) to shield cells from oxidative damage and maintains redox homeostasis [12]

doi: 10.3390/nu11020433 165 ZhongQGuoYFangXZhangJWangLZhaoLet al