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By combining insights from macro-scale biomechanics and molecular-level studies, researchers can develop more effective interventions to protect and repair the ACL

& Hernandez-Gea, V

Given the effect of PPAR on lipoprotein metabolism, it could be speculated that declining PPAR levels with NAFLD progression [75, 86] contribute to lower MTTP levels and apoB100 secretion rates

this pathway will, in turn, upregulate pro-fibrogenic matrix metalloproteinase-2 (MMP2) and downregulate matrix metalloproteinase-1 (MMP1), two enzymes responsible for remodeling the hepatic extracellular matrix [9, 191, 192, 216]

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