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In addition, in several studies, NAD depletion enhanced cancer cell susceptibility to oxidative stress through a reduction in antioxidative capacity by downregulating antioxidant proteins

rhamnosus CU01 was reported to have ~ 14 mol/g GSH when grown in MRS broth largely expected to be imported from the medium [34] but it does possess a gshF homolog

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But certain populations need a tailored approach

Additionally, C/EBP modulates the expression of immunosuppressive genes, including Arginase-1 and Nitric oxide synthase 2, which are essential for MDSC function [82]