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References Abdelgadir H.A., Van Staden J

The resulting damage from high glucose levels further increases oxidative stress, creating a cycle that can lead to complications like neuropathy, nephropathy, and retinopathy

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Novel mechanisminformed therapeutic approaches, such as bloodbased and microbiometargeted interventions are examined, reflecting a growing focus on systemic disease modulation

Additional information Peer review information Nature Communications thanks Rohini Kuner, Sabine Lvi and the other, anonymous, reviewer(s) for their contribution to the peer review of this work