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In this example and in type 1 diabetes, it has been discussed whether the normalization of glucose metabolism following rhIGF-I therapy is most importantly associated with insulin-like effects of IGF-I on glucose uptake in muscle or suppression of GH hypersecretion

The gut microbiome structure is affected by environmental stress in fish (Bagi et al., 2018)

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7.6 Properties of Phellodendron amurense polysaccharides and application of nano-carriers Phellodendron amurense polysaccharide (PIP) has demonstrated the ability to improve the intestinal microenvironment by modulating gut microbiota and enhancing mucosal immunity (237)

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