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Conversely, excessive ROS oxidize and damage cellular components, leading to cellular death (Luo et al., 2020

Given that core metabolic processes, including nucleotide synthesis, glycolysis, and redox defense, are fundamentally shared with normal proliferative tissues, broad-spectrum metabolic inhibition often lacks true selectivity and precipitates dose-limiting systemic toxicities [43]

This will hopefully prove particularly useful in the analysis of circulating steroids, making it possible to rigorously evaluate the role of CYP-mediated estrogen metabolism Citation[24] and facilitate the development of new models of breast cancer risk Citation[25]

First, the IL-6 level, a blood inflammation marker, showed a peak immediately after surgery and decreased thereafter, but it decreased more rapidly in the CT group and became significantly lower compared with the P group on Day 4 after surgery