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Severe side effects of High-dose glutathione IV include severe allergic reactions, kidney dysfunction, and liver dysfunction

References This article draws on peer-reviewed pharmacokinetic and clinical research on oral glutathione bioavailability and safety, established nephrology literature on renal glutathione physiology and oxidative stress, published data on N-Acetyl Cysteine (NAC) in contrast-induced nephropathy prevention, and India's CDSCO public advisory on injectable glutathione (issued May 18, 2026)

In BCC, TP53 mutations primarily occur as C-T transitions, and there is a prominent occurrence of the double base change from CC to TT, suggesting that these alterations are caused by exposure to UVR (164)

Cytosolic gamma-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis

These findings indicated that EGCG-Zn retained the antioxidant and DNA-protective properties of EGCG in normal intestinal epithelial cells while not compromising the cytotoxic efficacy of radiotherapy against malignant cells in the tested cancer cell line