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ROS, as natural metabolic byproducts, have been shown to damage nucleic acids, proteins, and lipids through mechanisms such as DNA mutations, lipid peroxidation, and altered post-translational modifications, ultimately compromising cellular integrity

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Michaelis K, Hoffmann MM, Dreis S, Herbert E, Alyautdin RN, Michaelis M, et al

This is because Cd can bind to estrogen receptors in cells and mimic the effects of estrogens

The Center for Drug Evaluation and Research (CDER) also published its annual Drug Trials Snapshots Summary Report, intended to provide healthcare professionals and consumers with information on the demographics of participants in FDA-approved drug clinical trials and where the trials were conducted