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Am J Vet Res , 2002

Cilostazol (Cls), a specific phosphodiesterase type-3 inhibitor, inhibits the degradation of cAMP, increasing its intracellular level, and subsequently activates protein kinase A

However, one must balance this with not eating too heavily or too late at night ( Dietary polyphenols and antioxidant-rich foods are primarily addressed as components of dietary patterns that support physiological resilience and redox balance during aging

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199 A randomized placebo-controlled trial in 24 fibromyalgia patients found a magnesium malate supplement providing 150 mg of elemental magnesium and 600 mg of malic acid twice daily for four weeks did not significantly affect pain