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SKU: 92161414549
Price: 28.25 USD
Availability: InStock
Rating: 4.8865 (26 reviews)

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SKU: 92161414549 · From www.ohotnichi-sezoni.com

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Description

While generally safe, certain individuals should avoid AOD-9604, including: Pregnant or breastfeeding women Due to limited safety data

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It was identified through a medicinal chemistry programme at the University of Texas Health Science Center as the lead NNMT inhibitor candidate among a series of 1-methylquinolinium analogues bearing primary amine substitutions, selected for its combination of high passive membrane permeability (confirmed in PAMPA assays), high active transport membrane permeability (confirmed in bidirectional Caco-2 cell assays), potent NNMT inhibitory activity, and high selectivity including confirmed absence of inhibitory effects on related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway