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only one report of mild scalp itching in the active group across the entire 6-month trial Combined delivery approach: First study to test copper tripeptide serum delivered via nano-fractional radiofrequency for male pattern hair loss Pilot-scale evidence: This was a small proof-of-concept study (6 patients) the results are promising but need confirmation in larger trials All patients completed treatment: 100% retention across both groups over 6 months, suggesting excellent tolerability Evidence Summary About This Study Medical Disclaimer: This article summarises published clinical research for educational purposes only

Serious adverse reactions are rare but may happen in sensitive individuals

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The histidine residue gives GHK an unusually strong affinity for copper, and the peptide is generally understood to act as a copper shuttle moving the metal between plasma proteins and cells