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Podratz Jewel L, Han L, Knorr P et al (2016) Cisplatin induces mitochondrial deficits in Drosophila larval segmental nerve

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How They Work at the Cellular Level CoQ10: Works inside mitochondria Directly involved in energy production processes Astaxanthin: Spans across cell membranes Helps protect both the inner and outer parts of the cell from oxidative damage Simple takeaway: CoQ10 powers the cell, while Astaxanthin helps protect it

p53 is associated with weight loss retention in obese humans To interrogate the translational relevance of our findings, we stratified diabetic patients undergoing three cycles of a fasting-mimicking diet (FMD 37 ) according to a metabolically relevant single nucleotide polymorphism (SNP) in p53 at amino acid 72 (rs1042522), encoding for either an arginine (R72) or a proline (P72) 38,39