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The crystal structure and AlphaFold-based analysis of LET7 revealed the interface between LET7 PPase and LET7 TPR mediated by several hydrogen bonds 25 (Extended Data Fig

This translocation of bacteria is implicated in immune activation and autoimmunity

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The early diagnosis of RA is often challenging due to the widespread symptoms reported by patients, including pain, swelling, stiffness, and functional impairment, many of which are also associated with other inflammatory diseases (Gibofsky 2014)