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Sotalol and acebutolol can produce QTc prolongation due to potassium channel blockade, which may result in torsades de pointes (63)

2329 mmol/L))

doi: 10.3390/cells8091101

This damage can result in mutations within oncogenes such as RAS and MYC, as well as tumor suppressor genes like p53 and PTEN, thereby fostering genomic instability and malignant transformation [31, 32]

The observation of intracellular accumulation of HNE-specific epitopes in human SLE for the first time raised the possibility that the higher lipid peroxidation may be directly involved in the pathogenesis of autoimmune disorders