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However, in the Adams 2011 study, there were only 3 participants out of 72 in the treatment group (4%) who dropped out of the study due to adverse effects, which suggests that this bias is probably modest

However, quinolinic acid is an agonist of NMDA (74, 75)

Enhanced potency of GalNAc-Conjugated antisense oligonucleotides in hepatocellular cancer models