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Aristeidis Katsanos: Nothing to disclose

However, this is an off-label, unvalidated approach

For those with heart failure, thiamin status should not be ignored, especially when the patient is on diuretics, has poor nutrition, has a history of alcohol use, has gut disease, has chronic diarrhea, has had bariatric surgery, or has unexplained worsening symptoms

Although the anatomical attributes of the nasal cavity significantly amplify drug absorption and facilitate rapid therapeutic responses, the formulation characteristics of intranasal drug delivery are equally crucial for achieving optimal therapeutic outcomes (Illum, 2003

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