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Many clinical trials targeting TAAs with vaccines have shown detectable immune responses, but these responses often lack the strength needed to produce significant clinical efficacy

Procaccini C, De Rosa V, Galgani M, Carbone F, Cassano S, Greco D, Qian K, Auvinen P, Cal G, Stallone G, Formisano L, La Cava A, Matarese G

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125,157 Diagnostic approaches include pupillometry for objectively measuring pupil size and reactivity, pharmacological testing to assess responses to agents like pilocarpine, and dynamic pupillometry as a non-invasive biomarker for autonomic dysfunction