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The animals were sacrificed by cervical dislocation under anesthesia with an i.p

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Vitamin B12 and folate play important roles in DNA methylation since these two coenzymes are required for the synthesis of methionine and S-adenosyl methionine, the common methyl donor required for the maintenance of methylation patterns in DNA

[4] Historically, many different terms have been used to refer to recurrent aphthous stomatitis or its sub-types, and some are still in use

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