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Our data support the hypothesis that -synuclein contributes to oxidative stress through a pathway that induces complex microglial activation as well as antioxidant responses and in addition requires a specific protein structure (Fig

Forkhead box protein O (FOXO) transcription factors play an important role in cell proliferation, apoptosis, autophagy, metabolism, inflammation and differentiation by activation or inhibition of downstream target genes 5

NAC has direct antioxidant activity but also increases intracellular levels of cysteine which facilitates GSH synthesis [45]

2026 Apr 30;189(9):2648-2662.e19

Interactions between SNPs were examined by logistic regression to analyze their combined effects on Hg levels and kidney function biomarkers