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Using PASS 15.0 statistical software (NCSS LLC, Kaysville, UT, USA) for analysis, with a Type I error of 0.025 and a power (1-) of 0.8 (one-sided), and setting = 0, the required sample size was determined to be 23 participants

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It produced the largest weight reductions observed in any pharmacotherapy prior to Retatrutide, reshaping expectations for what the best peptides for weight loss can achieve

The study found that serum B12 levels were comparable, and in some cases higher, among those using the sublingual supplement (1)