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The excess solvent was removed under reduced pressure to give lipoyl alanine (LA-Ala) as a light-yellow oil (70%) as a mixture of diastereomers

Dotterud & Falk, 1995)

Miyagi, A

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

In order to further increase the production of GSH, the addition of amino acid precursors (5 mM glutamic acid, 5 mM cysteine and 5 mM glycine) was single shot after 36-h cultivation for feeding assay