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Statistical analysis Data were analyzed using SPSS (version 25, Chicago, IL, USA)

After joint re-alignment, the muscle may stay activated, including maintaining muscle facia stretch, keeping the fascia tight, restricting the muscle from loosening, and causing pain from the proprioceptive and sensory nerve endings found in fascia

GR: Investigation, Supervision

Peripheral blood samples were analyzed for concentrations of metalloproteinase (MMP)-9, tissue inhibitors of MMP (TIMP)-1,2, and myeloperoxidase (MPO)

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