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(61) reported that vitamin D supplementation lowers the expression of TLR2, TLR4, and TLR9 in monocytes during autoimmune disease

Simona Cavalu, [email protected] ORCID: Abdullah Al Mamun, orcid.org/0000-0001-9936-3925 This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, it is becoming increasingly evident that autophagosomes can selectively engulf substrates including aggregate-prone proteins (aggrephagy) 61 , dysfunctional mitochondria (mitophagy) 62 and the endoplasmic reticulum (ER-phagy) 63

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Supplementary Video 10 (download MOV Example of a shrinking Single Color Area (SCA)