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Clinical and neurochemical correlates of the APOE genotype in early-stage Parkinsons disease

It is performed by a two-step process, in which amino acids are first activated by ATP, forming an intermediate aminoacyl adenylate, and then transferred to the 3-end of tRNA to form the end-product

10.1016/j.cmet.2020.01.009 56 HeL.WangJ.YangY.LiJ.TuH

Patients with GT-D virus had the lowest mean HBsAg level at baseline (2.97 log IU/mL) and GT-B the highest (3.76 log IU/mL)

These numbers exceeded the Phase 2 results, partly because the trial ran longer (68 weeks versus 48 weeks) and partly because the dose escalation schedule was refined