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In our targeted single cell RNA-sequencing experiment, we observed that after 6 months of zinc supplementation, naive CD8+ T cells increased the expression of genes associated with maturation (PIK3IP, TRAC), differentiation and migration to the lymph nodes (CCR7) where they develop immune responses to novel viral or tumoral antigens

In cohort 1B, efficacy was greater according to PD-L1 expression: 63.2% (PD-L1 90% of cases) and other solid tumors, implicated in their pathogenesis and invasiveness [84-86]

Techniques such as MRS and PET imaging have been used to detect glutamate changes and to quantify NMDARs and AMPARs in the autistic brain, but the utilization of GluCEST imaging in patients with autism remains to be studied