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This work is published and licensed by Dove Medical Press Limited

This is not a rare mutation, but rather a common variant that causes a change in how the gene functions

In pregnancy, hyperthyroidism may occurs because Beta-HCG can act on TSH receptors, producing more thyroid hormone

In routine practice, screening for vitamin B12 deficiency in patients with T2D on metformin therapy remains suboptimal, as indicated by a recent observational study [31]