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Subsequently, blood samples were collected to evaluate the pharmacokinetic parameters using high-performance liquid chromatography, and it was found that QUE significantly increased the plasma concentration of 5-FU and improved the availability of 5-FU (43)

Epub 2017 Aug 15

6 Khavinson, epigenetic peptides (PubMed)Proposed epigenetic mechanism of short peptides: binding to DNA and modulation of gene expression (preclinical / in-vitro)

This association is further substantiated by community-based cohort studies reporting that 42.3% of individuals without significant neurodegenerative pathology developed VCI, a progression primarily driven by severe cerebrovascular pathology (47)

Based on our results we cannot determine whether CBD directly affects CNS or if its effects are mediated through peripheral responses