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Moreover, CFZ treatment inhibited TLR2-and TLR4-mediated NF-B activation and TNF- production (122)

One is that GSSG and GS-X produced in cardiomyocytes are pumped out by multidrug resistance protein 1 (MRP1), preventing GSSG or GS-X accumulation in cardiomyocytes [33, 34], and subsequently enter the -glutamyl cycle

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