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doi: 10.3389/fendo.2024.1466775 Received 18 July 2024 Accepted 15 November 2024 Published 10 December 2024 Volume 15 - 2024 Edited by ke Sjholm, Gvle Hospital, Sweden Reviewed by Zhen Geng, Shanghai University, China Sanjiv Neupane, Stony Brook University, United States Updates Copyright 2024 Jia, Zhang and Yu

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Mouse Model For Studying The Efficiency Ofgenetic Vaccines In Transfecting Human Muscle Cells And Inducing Human Immune Responses In Vivo There is a lack of suitable in vivo models for studies of the efficiency of genetic vaccines and the vast majority of studies are performed on the mouse model, in which it is sometimes difficult to predict whether the results obtained reliably predict similar vaccinations in humans because of the complexity of events occurring after genetic vaccination A lack of suitable in vivo models has hampered studies of the efficiency of genetic vaccines in inducing antigen expression in human muscle cells and in inducing specific human immune responses