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Conclusions and perspectives By integrating mechanistic insights and disease-specific evidence, this review delineated how ATFs orchestrate macrophage development, survival, migration, phagocytosis, activation, cytokine secretion and polarization and how these regulatory axes converge to shape macrophage-driven pathology in infectious, inflammatory, metabolic, oncologic and neurodegenerative settings

2.2.2 Inflammation Inflammation is caused by fibrin clot formation and aggregated platelet degranulation (Pazyar et al., 2014)

doi: 10.1016/j.aninu.2020.01.001 56 Kumar SenASenDBZanwarASBalaramanRShahUMaheshwariRA

However, the expression of AtGHR1 is also increased by hypoxia, while AtGHR3 is increased in response to salt treatments and increases in light