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This finding has important implications for the potential therapeutic applications of SFN, as the R enantiomer may offer enhanced benefits [128]

The KD has been utilized as a therapeutic approach for a considerably longer period than BHB, whether BHB presents additional side effects requires further investigation

Franco R., Li S., RodriguezRocha H., et al., Molecular Mechanisms of Pesticideinduced Neurotoxicity: Relevance to Parkinson's Disease, ChemicoBiological Interactions 188, no

Under stress conditions, mitochondrial damage results in the production of excessive mtROS, provoking oxidative damage to mtDNA and mtDNA release into the cytoplasm through the mitochondrial permeability transition pore, which further activates the DNA sensor cGAS-STING and facilitates downstream inflammatory processes (101, 102)

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