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However, high-dose niacin (as a medication for cholesterol) is generally not recommended during breastfeeding, because significant amounts could enter milk and cause unwanted effects in the nursing infant (flushing, for example)

Others might observe that the effects begin to lessen

[5] The primary contraindication for hydroxocobalamin injection is a known hypersensitivity to hydroxocobalamin, cobalt, or any component of the formulation

Kassem HS, Sangar V, Cowan R, Clarke N, Margison GP (2002) A potential role of heat shock proteins and nicotinamide N-methyl transferase in predicting response to radiation in bladder cancer

That said, alcohol can impair judgment about injection technique, interfere with sleep and recovery, add empty calories that work against fat loss goals, and contribute to dehydration that may worsen side effects like headaches