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In traumatic injuries (neurotrauma, neuroinfection, stroke or immune attack), irreversible proliferative astrogliosis is essential for wound closure and formation of a glial border that separates fibrotic scar tissue from the healthy neural tissue and promotes postlesional regeneration

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinsons disease

Oxidative stress: The accumulation of free radicals can accelerate skin aging, leading to problems such as wrinkles and pigmentation

To further confirm that the ferroptosis resistance of 4-OI was dependent on Nrf2, the siRNA against Nrf2 was constructed and successfully reduced Nrf2 levels in THP-1 cells (Fig

Table 3 Targets for protein S-thiolation by bacterial thiol-redox buffers