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Chimeric antigen receptor macrophage therapy for breast tumours mediated by targeting the tumour extracellular matrix

Figure 1 MiR-15a and miR-16-1, which belong to the same cluster of tumor suppressor miRNAs, were found to be down-regulated both in GH-secreting and prolactin-secreting pituitary adenomas ( A group of miRNAs have been found to be downregulated in GH secreting adenomas leading to the overexpression of proteins involved in pituitary tumorigenesis

However, its skin absorption remains challenging due to its hydrophilicity

ALA can also be synthesized de novo in mitochondria via lipoic acid synthase [27]