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Mitochondrial dysfunction is recognized as one of the primary hallmarks of biological aging, and MOTS-c directly addresses this mechanism

10.3390/ijms17122146 17 ChenP.ZhengL.WangY.TaoM.XieZ.XiaC.et al (2019)

Bortezomib induces the formation of nuclear poly(A) RNA granules enriched in Sam68 and PABPN1 in sensory ganglia neurons

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All outcomes were measured for both eyes except 1 eye that had another disease process that could affect visual function, but only 1 eye was selected for obtaining aqueous samples