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This clearly implies that, although several in vitro tests for genotoxicity assessment are available at different stages of development and acceptance, they cannot be considered to fully replace animal tests needed to evaluate the safety of substances (see Adler et al., 2011)

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Brezovsky J, Babkova P, Degtjarik O, Fortova A, Gora A, Iermak I, Rezacova P, Dvorak P, Smatanova IK, Prokop Z, Chaloupkova R, Damborsky J (2016) Engineering a de novo transport tunnel

It laid the groundwork for the current study, exploring the complex links between antioxidants, health, and cancer

Glucuronidation accounts for the majority of APAP metabolic pathways in healthy adults ( The precise evaluation of complex human liver metabolism and toxicity may include in silico approaches as complementary or promising alternatives to existing in vivo and in vitro approaches