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doi: 10.1007/s13402-017-0354-4 461 ShechnerDMHacisuleymanEYoungerSTRinnJL

The increase in MG after H 2 O 2 stimulation may be significantly associated with increased glycolysis

HSCs, the primary producers of ECM, play an indispensable role in the pathogenesis of liver fibrosis ( The pathogenesis of liver fibrosis is complex, with sustained HSC activation and ECM deposition due to chronic liver injury being major contributors ( in vitro and animal models has revealed multiple pathways by which glycyrrhizin inhibits HSC activation