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The significant role of OS in the pathogenesis of ALS and its animal model has been established for years, on the basis of which inducing sufficient antioxidant production and improving the bodys antioxidative stress ability were believed to be a promising target for ALS management ( SFI has been marketed as an antitumor auxiliary medicine as early as in the year 1999 in China and approved for clinical trials in the United States in 2018, which guaranteed its safety in clinical application

In total joint arthroplasty, where wound complications and periprosthetic joint infection carry substantial consequences, perioperative risk minimization should remain the priority