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Li Y, Chen Y, Yu P, Zhang D, Tang X, Zhu Z, et al

Bioorg Med Chem Lett 22:18221826

From mechanism to phenotype: What fits in a basket trial

New horizons to continue exploring UDCA in DILI Although UDCA is not currently strongly recommended as a therapeutic option in DILI, most guidelines acknowledge its potential benefits, particularly in cholestatic-DILI patients (Table 1)

Retrospective cohort analyses show that among patients with metastatic disease, lung metastasis is diagnosed in 7585% of osteosarcoma, 45.2% of RCC, 39.5% of HCC, 31.7% of CRC, 2132% of BC, and 5% of melanoma patients (Fig