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Epigenetic modifications also impair the function of antioxidant defense genes, including SOD and nuclear factor erythroid 2-related factor 2 (Nrf2), thereby worsening -cell dysfunction and oxidative damage [29-31]

ROS activate receptor tyrosine kinases (RTKs) via oxidative modification, which in turn leads to the activation of MAPKs (66)

In addition, we applied the proposed MS-DRG reclassification and recalibration budget neutrality adjustment factor before the cap (derived in the first step) to the payment rates that were used to simulate payments for this comparison of aggregate payments from FY 2023 to FY 2024

N-Acetylcysteine (NAC), a precursor of GSH, helps sustain redox homeostasis and mitigates oxidative damage

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