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The methylation profile of the tumor was compared with previously defined methylation classes using the publicly available database of the German Center for Cancer Research (DKFZ) (Figure 4A) (Figure 4B) ( Figure 4 Interestingly, the sarcoma classifier showed a match in the primary tumor for soft tissue clear cell sarcoma (Score: 0.96), but EWSR1/CREB1 or ATF1 gene fusion were excluded

The appearance of a halo is believed to correlate with the onset of nevus regression and eventual disappearance of the nevus

Cinotti E, Campoli M, Pataia G, Ouerdane Y, Thuret G, Gain P, et al

The British Association of Dermatologists says it is now on the alert for patients with warning signs of unusual orange tans and disordered moles

A mcula melantica uma alterao pigmentada plana, bem circunscrita, de colorao marrom ou negra, de etiologia desconhecida ou reacional