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For co-immunoprecipitation (Co-IP), HEK293T cells were co-transfected with pCMV-HA or pCMV-HA-Ss72 and pcDNA6-N-3XFlag-GSK3 (Addgene, #123592)

Some peaks overlapped genes with products linked to insecticide resistance, including cytochrome P450 4 , glutathione S-transferase 1 , acetylcholinesterase 6 , UDP-glycosyltransferase 52 , esterase B1 50 , Nach sodium channel protein 3 , xanthine dehydrogenase 57 , and phenoloxidase-activating factor 58

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Immunotherapy targeting HER2 with genetically modified T cells eliminates tumor-initiating cells in osteosarcoma